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GROUP IV PHOSPHOLIPASES A2
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DeCS
Descriptor
English
:
Group IV Phospholipases A2
Descriptor
Spanish
:
Fosfolipasas A2 Grupo IV
Descriptor
Portuguese
:
Fosfolipases A2 do Grupo IV
Synonyms
English
:
Phospholipases A2, Group IV
Tree Number:
D08.811.277.352.100.680.750.937.625.249
Definition
English
:
A cytosolic phospholipase A2 group that plays an important role in the release of free
ARACHIDONIC ACID
, which in turn is metabolized to
PROSTAGLANDINS
by the CYCLOOXYGENASE pathway and to
LEUKOTRIENES
by the
5-LIPOXYGENASE
pathway.
Indexing Annotation
English
:
/antag: coordinate with
PHOSPHOLIPASE A2 INHIBITORS
History Note
English
:
2008(1997)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52666
Unique Identifier:
D054513
Occurrence in VHL
:
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DeCS
CID-10
SciELO
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